ea0025p119 | Cytokines, growth factors, neuroendocrinology and behaviour | SFEBES2011
Gupta Saket
, Maratha Ashwini
, Gajanayake Thusitha
, Siednienko Jakub
, Natarajan Anandan
, Hoashi Shu
, Miggin Sinead
Inflammation is a component of obesity-associated insulin resistance. Significant increases in inflammatory mediators such as IL6, TNFa and IL1b have been detected in the serum of diabetic patients. Herein, we investigated whether pre-diabetic patients also exhibited perturbations in circulating pro-inflammatory cytokines. To this end, we recruited 42 healthy non diabetics and subjected them to 75 g OGTT after an overnight fast. We profiled the cytokines that are present in th...